PUBLICATIONS

Novel Cell-Ess ® supplement used as a feed or as an initial boost to CHO serum free media results in a significant increase in protein yield and production<

Abstract

Many metrics, including metabolic profiles, have been used to analyze cell health and optimize productivity. In this study, we investigated the ability of a lipid supplement to increase protein yield. At a concentration of 1% (v/v) the lipid supplement caused a significant increase in protein titer…
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Peer Reviewed Publication

Providing Lipids Boosts Protein Productivity:  Testing a Feed Supplement with Multiple Cell Clones and Media Formulations

Abstract

We sought to determine whether Cell-Ess media containing lipids can be used across different serum-free media and different stably transfected CHO clones to attain increased titer. In addition, we discuss the important of study design, specifically related to when and how protein output is measured. Attention paid to these nuances in study design ensures that results truly indicate what can be expected in a biomanufacturing environment…
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